Phenylmethanesulfonyl Fluoride, 250 mg, Un 2928 6.1/pg 2, Each

Details:

Specifications synonyms: alpha-toluenesulfonyl fluoride; benzylsulfonyl fluoride; pmsf; phenylmethylsulfonyl fluoridecas number: 329-98-6formula: c7h7fo2sformula weight: 174.19Linear formula: c7h7fo2smdl no.: Mfcd00007424purity: >=98.5% (Gc)beilstein registry number: 2088311ec number: 206-350-2unspsc code: 12352202application: inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. Not as effective or as toxic as dfp. Effective concentration 0.1-1 Mm. Half-lifeâ =â 1 hr. At ph 7.5.Application: phenylmethanesulfonyl fluoride has been used in following applications:. Cell fractionation.. Used as a supplement in nuclear protein extraction.. Inhibitor of cholesterol esterase (ce) and pseudocholinesterase (pce).. Used for the collection of blood prior to centrifugation to quantify plasma anp levels.Biochem/physiol actions: administration of pmsf produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered î²-endorphin.Rtecs: xt8040000ridadr: un 2928 8(6.1) / Pgiiwgk germany: 3r codes: 25-34s codes: 26-36/37/39-45iod codes: tsymbol: ghs05, ghs06signal word: dangerhazard statements: h301-h314precautionary statements: p280-p301 p310 p330-p303 p361 p353-p304 p340 p310-p305 p351 p338