Socs1 Rabbit Anti-Human, Mouse, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Socs1, Each

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This gene encodes a member of the stat-induced stat inhibitor (ssi), also known as suppressor of cytokine signaling (socs), family. Ssi family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including il2, il3 erythropoietin (epo), csf2/gm-csf, and interferon (ifn)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of ifn-gamma action, which is required for normal postnatal growth and survival. [Provided by refseq