Sox2 Mouse, Alexa Fluor 647, Clone: 245610, Bd, Mouse Monoclonal Antibody, Each

Details:

The monoclonal antibody 245610 recognizes the sox2 transcription factor. Sox2 (sry (sex determining region y)-box 2) is a member of the sry-related hmg-box (sox) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of sox2 with the homeobox transcription factors oct3/4 and/or nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. The 245610 antibody recognizes both human and mouse proteins. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain.