Stat2 Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Stat2, Each

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The protein encoded by this gene is a member of the stat protein family. In response to cytokines and growth factors, stat family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (ifn), this protein forms a complex with stat1 and ifn regulatory factor family protein p48 (isgf3g), in which this protein acts as a transactivator, but lacks the ability to bind dna directly. Transcription adaptor p300/cbp (ep300/crebbp) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking ifn-alpha response by adenovirus. [Provided by refseq