Syntaxin 6 Mouse, Unlabeled, Clone: 30, Bd, Mouse Monoclonal Antibody, Each

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Signal transmission between cells is often regulated by the secretion of neurotransmitters or hormones into the extracellular space. This process is controlled by a complex pathway of membrane trafficking which leads to membrane fusion and secretion. Syntaxin 1 is involved in three important complexes that modulate the secretion process: syntaxin and n-sec-1, syntaxin, vamp, and snap-25, and syntaxin, vamp, snap-25, αsnap, and nsf (20s complex). Syntaxin 6 is a 255 amino acid member of the syntaxin family. It contains a c-terminal transmembrane domain and is located at the golgi apparatus. In addition, syntaxin 6 displays significant (47% identity) homology with snap-25. In vitro, syntaxin 6 has been reported to interact with α-snap. Syntaxin 6 has been reported to have a calculated molecular weight of 30.6Kda, but has been observed to migrate in a range inbetween ∽ 31-35kda.Immunofluorescence, immunohistochemistry, immunoprecipitation, western blotting