Tcr Β Chain Hamster Anti-Mouse, Unlabeled, Clone: H57-597, Bd, Hamster Monoclonal Antibody, Each

Details:

The h57-597 antibody reacts with a common epitope of the β chain of the t-cell receptor (tcr) complex on αβ tcr-expressing thymocytes and peripheral t lymphocytes and nk1.1+ Thymocytes and nk-t cells of all mouse strains tested. It dodoes not react with γδ tcr-bearing t cells. In the fetal and adult thymus, the tcr β-chain may form homodimers or pair with the pre-tcr α-chain on the surface of immature thymocytes before expression of the tcr α-chain. Plate-bound or soluble h57-597 antibody activates αβ tcr-bearing t cells, and plate-bound mab can induce apoptotic death.