Cd117/C-Kit/Scf-Receptor Ab-3 Mouse Monoclonal Antibody, Obtain Accurate, Reproducible Results In Immunohistochemistry And Immunofluorescence Experiments, Each

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C-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (scf). It is expressed in many tissues and cells. C-kit/scf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells. Ab-3 does not interfere with the binding of scf to c-kit host species: mouseclone: k45isotype: igg2aspecies reactivity: human. Others not known.Epitope: extracellular second n-terminus ig-like domain of c-kitimmunogen: recombinant human extracellular c-kit fragmentmolecular weight: 145kdapositive control: skin, gi stromal tumor (gist)cellular localization: membrane/cytoplasmicrecommended for:immunohistochemistry (frozen or fixed in methacarn or stieve's and embedded in paraffin)immunofluorescence note:usa: ruo; int'l: ruo