Her-3/C-Erbb-3 Ab-2 Mouse Monoclonal Antibody, Her-3/C-Erbb-3 Ab-2, Mouse Monoclonal Antibody Provides Accurate, Reproducible Results, Each

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C-erbb-3/her-3 is the third member of the type i family of growth factor receptors. It binds to ligands in the heregulin family. C-erbb-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & egf stimulate tyrosine phosphorylation of c-erbb-3 to different extents. Host species: mouseclone: 2f12isotype: igg2a/κspecies reactivity: human, cow, rat and mouse. Others not tested.Epitope: aa 1295-1323immunogen: recombinant rat her-3/c-erbb-3 oncoproteinmolecular weight: 185kdapositive control: t47d cellscellular localization: cytoplasmic and membrane recommended for:western blottingimmunoprecipitation (native and denatured) note:usa: ruo; int'l: ruo