53 Ab-5 Mouse Monoclonal Antibody, Achieve Accurate, Reproducible Results With The P53 Ab-5, Mouse Monoclonal Antibody, Each

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53 Is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, sv40 t antigen and human papilloma virus e6 protein p53 senses dna damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host species: mouseclone: do-7isotype: igg2b/κspecies reactivity: human, monkey, cow. Others not known.Epitope: aa 37-45immunogen: recombinant human wild-type p53 protein expressed in e. Colimolecular weight: 53kdapositive control: skbr-3 or mda-231 cells, colon cacellular localization: nuclear recommended for:immunohistochemistry (formalin/paraffin)western blottingimmunofluorescenceimmunoprecipitation (denatured verified)flow cytometry