53 Ab-6 Mouse Monoclonal Antibody, Achieve Accurate, Reproducible Results With The  P53 Ab-6, Mouse Monoclonal Antibody, Each

Details:

53 Is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, sv40 t antigen and human papilloma virus e6 protein p53 senses dna damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. Host species: mouseclone: do-1isotype: igg2aspecies reactivity: human, monkey and cow. Reacts weakly with mouse and rat. Others not known.Epitope: aa 11-25immunogen: recombinant human wild-type p53 protein expressed in e. Colimolecular weight: 53kdapositive control: skbr-3 cells or mda-231 cells, colon cacellular localization: nuclear recommended for:immunohistochemistry (formalin/paraffin)western blottingimmunofluorescenceimmunoprecipitation (native and denatured)flow cytometrygel supershift assay note:usa: ruo; int'l: ruo