Lab Vision Pax-5 Rabbit Monoclonal Antibody, Take Advantage Of Part Of A Comprehensive Antibody Portfolio With The Pax-5, Rabbit Monoclonal Antibody, Each

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Pax-5 is a b-cell-specific activator protein (bsap). In the early stages of b cell developmemt, pax-5 influences the expression of several b-cell-specific genes, such as cd19 and cd20. Pax-5 is expressed primarily in pro-, pre-, and mature b cells, but not in plasma cells. Pax-5 is expressed in most b-cell malignancies (pre-b and mature b cell lymphomas/leukemias). Over 90% of cases are positive for pax-5 in hodgkin's lymphoma, lymphoplasmacytic lymphoma, merkel cell and small cell carcinoma. T-cell lymphomas, myeloma/plasmacytoma and carcinoid tumors are negative for pax-5. Host species: rabbitclone: sp34isotype: iggspecies reactivity: human. Others not tested.Immunogen: synthetic peptide derived from the c-terminus of human pax-5 proteinmolecular weight: 50kdapositive control: tonsilcellular localization: nuclear recommended for:immunohistochemistry (formalin/paraffin)