Lab Vision Pax-5 Rabbit Polyclonal Antibody With Bsa And Azide, Provide Accurate, Reproducible Results With The Pax-5, Rabbit Polyclonal Antibody, Each

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Pax-5 is a b cell specific activator protein (bsap). In the early stages of b cell developmemt, pax-5 influences the expression of several b-cell-specific genes, such as cd19 and cd20. Pax-5 is expressed primarily inpro-, pre-, and mature b cells, but not in plasma cells. Interestingly, pax-5 mrna is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of b lymphopoiesis. This indicates that pax-5 is important in b cell development, but may also have a role in proper neuronal development.Host species: rabbitspecies reactivity: human, mouse, rat. Others not tested.Epitope: c-terminalimmunogen: synthetic peptide derived from c-terminus of human pax-5 proteinmolecular weight: 50kdapositive control: tonsil, raji cellscellular localization: nuclearrecommended for:immunohistochemistry (formalin/paraffin)western blotting