Timp-2 Ab-5 Mouse Monoclonal Antibody, Provide Accurate, Reproducible Results With The Timp-2 Ab-5, Mouse Monoclonal Antibody, Each

Details:

Timp-1 and timp-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. Timp-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kda type iv collagenase (also known as mmp-2 or gelatinase a). It also has affinity for the active form of 92kda type iv collagenase (also known as mmp-9 or gelatinase b). Timp-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Host species: mouseclone: 3a4isotype: igg2a/κspecies reactivity: human, mouse, rat, rabbit, cow and guinea ppig. Others not known.Epitope: n-terminalimmunogen: a synthetic peptide from the n-terminal region of human timp-2 proteinmolecular weight: 21kdapositive control: conditioned, serum-free medium from (tpa-treated) hfl-1 cells; pancreatic or colon cacellular localization: cytoplasmic recommended for:immunohistochemistry (formalin/paraffin only)western blottingimmunoprecipitation (not suitable) note:usa: ruo; int'l: ruo