Transglutaminase Ii Ab-1 Mouse Monoclonal Antibody, Transglutaminase Ii Ab-1, Mouse Monoclonal Antibody Provides Accurate, Reproducible Results, Each

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Transglutaminase ii catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as tgc, ttg, type ii-, gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing. Host species: mouseclone: cub 7402isotype: igg1/κspecies reactivity: human, dog, rabbit and guinea pig. Does not react with mouse and rat. Others not known.Epitope: aa 447-478immunogen: purified guinea pig liver tgase iimolecular weight: 77-85kdapositive control: huvec cells, breast cacellular localization: cytoplasm, membrane and extracellular matrix ab-1 inhibits the tgase ii activity. Recommended for:immunohistochemistry (formalin/paraffin)western blottingimmunofluorescenceimmunoprecipitation (native and denatured)affinity purificationbiological blockade note:usa: ruo; int'l: ruo