Tnf Mouse Anti-Human, Pe-Cy7, Clone: Mab11, Bd, Mouse Monoclonal Antibody, Each

Details:

The mab11 monoclonal antibody specifically binds to human tumor necrosis factor (tnf, also known as tnf- α ) protein. Tnf is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. Tnf is cytotoxic for transformed cells when in conjunction with ifn- γ. It is secreted by activated monocytes/macrophages and other cells such as b cells, t cells and fibroblasts. The immunogen used to generate the mab11 hybridoma was recombinant human tnf. The mab11 antibody has been reported to crossreact with rhesus macaque tnf.