Tnfrsf21 Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Recombinant Tnfrsf21, Each

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The protein encoded by this gene is a member of the tnf-receptor superfamily. This receptor has been shown to activate nf-kappab and mapk8/jnk, and induce cell apoptosis. Through its death domain, this receptor interacts with tradd protein, which is known to serve as an adaptor that mediates signal transduction of tnf-receptors. Knockout studies in mice suggested that this gene plays a role in t-helper cell activation, and may be involved in inflammation and immune regulation. [Provided by refseq