Asp 2535, Potent And Selective Glyt1 Inhibitor, Each

Details:

Asp 2535 is a potent and selective glyt1 inhibitor (ic50 = 92 nm). Exhibits 50-fold selectivity over glyt2. Attenuates mk 801 -induced working memory deficits and pcp -induced visual learning deficits in mice. Orally available and brain penetrant.