Gsk 5959, Potent And Selective Brpf1 Inhibitor, Each

Details:

Gsk 5959 is a potent and selective brpf1 bromodomain inhibitor (ic50 = 80 nm). Exhibits >100-fold selectivity for brpf1 over a panel of 35 other bromodomains, including brpf2/3 and bet family bromodomains. Inhibits brpf1 interaction with histone h3.3. Cell permeable.