Ppq 102, Potent, Voltage-Independent Cftr Chloride Channel Inhibitor, Each

Details:

Ppq 102 is a potent, voltage-independent cftr chloride channel inhibitor (ic50 = 90 nm). Reduces the size and number of renal cysts in an embryonic kidney culture model of polycystic kidney disease. Also increases vegf-a production from airway epithelial cells in vitro.