Ro 48-8071 Fumarate, 2,3-Oxidosqualene Cyclase (Osc) Inhibitor; Blocks Cholesterol Synthesis, Each

Details:

Ro 48-8071 fumarate is a 2,3-oxidosqualene cyclase (osc) inhibitor (ic50 = 6.5 Nm); blocks cholesterol synthesis in hepg2 cells. Reduces viability of breast cancer cell lines. Also inhibits ebola virus (ebov) cell entry (ic50 = 1.74 μM).