Sgx 523, Selective And Potent C-Met Kinase Inhibitor, Each

Details:

Sgx 523 is a potent and selective c-met kinase inhibitor (ic50 = 4nm). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 μm). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.