Ty 52156, S1p3 Receptor Antagonist, Each

Details:

Ty 52156 is a s1p3 receptor antagonist (ki = 110 nm); inhibits s1p-induced ca2 release in huvec cells. Suppresses fty-720-induced s1p3 receptor-mediated bradycardia in vivo. Also inhibits s1p-induced breast cancer stem cell expansion in vitro. Orally bioavailable.