Vivid Regeneration System, 100x, Vivid Regeneration System, 100x, Each

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Vivid™ regeneration system, 100x, is a vivid™ cyp450 screening kit component consisting of glucose-6-phosphate and glucose-6-phosphate dehydrogenase, which converts nadp into nadph, which is required to start the cyp450 reaction. Vivid™ regeneration system, 100x, is included in the vivid™ screening kits, but may also be purchased separately.More about vivid™ cyp450 screening kitsvivid™ cyp450 screening kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and cyp450 inhibition. Vivid™ cyp450 screening kits include vivid™ substrate, vivid™ fluorescent standard, reaction buffer, vivid™ regeneration system, nadp , and cyp450 baculosomes™ plus reagent. Vivid™ fluorogenic substrates are blocked dyes that yield minimal fluorescence signal until cleaved or hydroxylated. Oxidation at either of two potential sites releases the highly fluorescent product. Cyp450 baculosomes™ plus reagents are microsomes prepared from insect cells expressing a human cyp450 isozyme and human cytochrome p450 reductase. Cyp450 baculosomes™ plus reagents offer a distinct advantage over human liver microsomes in that only one cyp450 isozyme is expressed, thereby preventing metabolism by other cyp450s.>> View all vivid™ cyp450 screening kitsfor research use only. Not for any animal or human therapeutic or diagnostic use.