Zd 7155 Hydrochloride, Selective Non-Peptide At1 Antagonist, Each

Details:

Zd 7155 hydrochloride is a potent and selective competitive antagonist for the angiotensin ii type 1 (at1) receptor. Displaces [125i]-angiotensin ii binding with an ic50 value of 3.8 Nm in guinea pig adrenal gland membranes. Orally active, and is more potent and longer-acting than the prototype at1 antagonist, losartan.